Longevity & NAD+

Why senior dogs lose antioxidant reserve, what that looks like at home, and how food, movement, and vet-guided support fit together.

What shrinks, slows, and builds up in the aging dog brain — and how to support clarity, sleep, and memory with food-first care.

Why aging dogs make less melatonin at night, how sleep and repair shift, and what supports rest.

Why older dogs lose muscle even on the same food, how protein synthesis and breakdown shift with age, and what actually helps preserve strength.

Why older dogs make, recycle, and spend NAD+ differently, and how to support energy without overselling supplements.

A veterinary neurologist explains how researchers measure cognitive aging in dogs with questionnaires, memory tasks, and brain tracking.

Researchers measure frailty in dogs with frailty indexes, activity tracking, muscle and mobility checks, and owner questionnaires. Learn what each method captures.

A rehab specialist explains how aging studies track gait, strength, and daily function in dogs — and what those tests mean for your senior dog.

Why older dogs burn fewer calories at rest, how lean mass and mitochondria drive the shift, and how to feed for it.

A vet-led explainer on the NAD+ salvage pathway in dogs — NAMPT, NMN, sirtuins, muscle aging, and what supports healthy recycling.

Why food tryptophan is a weak NAD+ source for aging dogs, how the kynurenine pathway really works, and what supports mobility better.

A veterinary guide translating the 12 hallmarks of aging into plain-English signs and daily care steps for senior dogs.

A longevity-minded guide to adaptogens for senior dogs — HPA-axis biology, ashwagandha and ginseng evidence, safety tradeoffs, and a methodical way to trial them.

Autophagy is your aging dog's cellular cleanup system. Learn how it slows with age and what daily habits best support it.

A vet explains carotenoids in senior dogs — lutein, beta-carotene, lycopene and astaxanthin — what they do, what food-first dosing looks like, and when to pause.

Glycation stiffens proteins and slows recovery in senior dogs. Learn how steady movement, diet, and vet care help maintain comfort and mobility.

Hormesis is the biology of small, recoverable stresses that help maintain resilience in aging dogs — learn how movement, handling, and routine fit together.

mTOR controls growth versus cleanup in aging dog cells. Learn what shifts it, what supports balance, and what to prioritize.

Oxidative stress in senior dogs explained in plain English: what free radicals do to joints, muscle and mitochondria, and what actually helps.

A sports-medicine veterinarian explains polyphenols for aging dogs — what quercetin and resveratrol do at the cellular level, how gait and load connect, and what to prioritize.

Telomeres shorten as dogs age. Learn what that means for energy, recovery, and daily care, and what still helps most.

CD38 rises with age and drains NAD+ in dogs and people. Learn what it means for energy, recovery, and what owners can actually do.

Pet dogs share our homes, air, and routines — learn why longevity researchers study their aging to understand human health.

A vet's honest look at magnesium L-threonate for aging canine brains — the rodent data behind it, what's missing in dogs, and how it compares to other cognitive-support options.

A vet's mechanism-first look at PQQ supplements for dogs — what pyrroloquinoline quinone does at the cellular level, what's proven, what's still a hypothesis, and how to weigh safety.

A vet's evidence-bounded look at ginkgo biloba for canine cognitive dysfunction — what small trials show, where the bleeding-risk caveat matters, and how to weigh cost against access.

A vet-informed checklist for reading the real signs of declining quality of life in an aging dog, and how to tell a bad week from a genuine turning point.

A veterinarian explains why older dogs vocalize at nothing after dark — from cognitive dysfunction to pain to sensory loss — and what to rule out first.

A vet's evidence-based look at berberine for dogs — what the metabolic research actually shows, where the drug-interaction risk lives, and how it compares to gentler longevity antioxidants like quercetin and resveratrol.

A board-certified veterinary neurologist explains the early signals — from subtle thirst changes to gait shifts — that mean a senior dog's next visit should include a blood panel, not just a wait-and-see approach.

A line-by-line accounting of what NAD+ and cellular-aging supplements really cost across a full year, with an honest look at where Boops Pets and Leap Years each earn their price.

A veterinary neurologist explains why dog hind leg weakness is a symptom, not a diagnosis, and how to tell nerve-based causes from joint pain before you act.

A veterinarian's candid guide to NAD+ precursor chews for a dog whose energy dropped around age 8: the biology, the real human and canine evidence, and how to choose one.

Taurine deficiency can quietly weaken a dog's heart. Learn the early and urgent signs, which breeds and diets raise the risk, and when to test.

MCT oil can fuel an aging dog's brain with ketones, but is it safe for every senior dog with cognitive decline? A vet reviews the evidence and the cautions.

A newly jumpy senior dog usually has a physical cause — pain, hearing change, or cognitive aging. Here's how to work through it, and when to call the vet.

A veterinarian's evidence-led review of the best longevity supplement for senior dogs, comparing NAD+ precursors, antioxidants, third-party testing, and NASC oversight.

A veterinarian's evidence-based guide to why senior dogs slow down across the joints, brain, and cellular energy, and which supplements may help support each aging system.